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Crystal structure of a complex of Sse1p and Hsp70

Source organisms:
Biochemical function: ATP-dependent protein folding chaperone
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00012
Domain description: Hsp70 protein
Occurring in:
  1. Heat shock protein homolog SSE1
  2. Heat shock 70 kDa protein 1A
The deposited structure of PDB entry 3d2f contains 2 copies of Pfam domain PF00012 (Hsp70 protein) in Heat shock protein homolog SSE1. Showing 1 copy in chain A.
The deposited structure of PDB entry 3d2f contains 2 copies of Pfam domain PF00012 (Hsp70 protein) in Heat shock 70 kDa protein 1A. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR018181
Domain description: Heat shock protein 70, conserved site
Occurring in:
  1. Heat shock protein homolog SSE1
  2. Heat shock 70 kDa protein 1A
IPR043129
Domain description: ATPase, nucleotide binding domain
Occurring in:
  1. Heat shock protein homolog SSE1
  2. Heat shock 70 kDa protein 1A
IPR029048
Domain description: Heat shock protein 70kD, C-terminal domain superfamily
Occurring in:
  1. Heat shock protein homolog SSE1
IPR029047
Domain description: Heat shock protein 70kD, peptide-binding domain superfamily
Occurring in:
  1. Heat shock protein homolog SSE1
IPR013126
Domain description: Heat shock protein 70 family
Occurring in:
  1. Heat shock protein homolog SSE1
  2. Heat shock 70 kDa protein 1A

Structure domains

CATH CATH domains
3.30.420.40
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Nucleotidyltransferase; domain 5
Homology: Nucleotidyltransferase; domain 5
Occurring in:
  1. Heat shock protein homolog SSE1
  2. Heat shock 70 kDa protein 1A
The deposited structure of PDB entry 3d2f contains 4 copies of CATH domain 3.30.420.40 (Nucleotidyltransferase; domain 5) in Heat shock protein homolog SSE1. Showing 2 copies in chain A.
The deposited structure of PDB entry 3d2f contains 4 copies of CATH domain 3.30.420.40 (Nucleotidyltransferase; domain 5) in Heat shock 70 kDa protein 1A. Showing 2 copies in chain B.
3.90.640.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Actin; Chain A, domain 4
Homology: Actin; Chain A, domain 4
Occurring in:
  1. Heat shock protein homolog SSE1
  2. Heat shock 70 kDa protein 1A
The deposited structure of PDB entry 3d2f contains 2 copies of CATH domain 3.90.640.10 (Actin; Chain A, domain 4) in Heat shock protein homolog SSE1. Showing 1 copy in chain A.
The deposited structure of PDB entry 3d2f contains 2 copies of CATH domain 3.90.640.10 (Actin; Chain A, domain 4) in Heat shock 70 kDa protein 1A. Showing 1 copy in chain B.
3.30.30.30
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Defensin A-like
Homology: Defensin A-like
Occurring in:
  1. Heat shock protein homolog SSE1
  2. Heat shock 70 kDa protein 1A
The deposited structure of PDB entry 3d2f contains 2 copies of CATH domain 3.30.30.30 (Defensin A-like) in Heat shock protein homolog SSE1. Showing 1 copy in chain A.
The deposited structure of PDB entry 3d2f contains 2 copies of CATH domain 3.30.30.30 (Defensin A-like) in Heat shock 70 kDa protein 1A. Showing 1 copy in chain B.
1.20.1270.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Substrate Binding Domain Of Dnak; Chain:A; Domain 2
Homology: Substrate Binding Domain Of Dnak; Chain:A; Domain 2
Occurring in:
  1. Heat shock protein homolog SSE1
The deposited structure of PDB entry 3d2f contains 2 copies of CATH domain 1.20.1270.10 (Substrate Binding Domain Of Dnak; Chain:A; Domain 2) in Heat shock protein homolog SSE1. Showing 1 copy in chain A.
2.60.34.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Substrate Binding Domain Of DNAk; Chain A, domain 1
Homology: Substrate Binding Domain Of DNAk; Chain A, domain 1
Occurring in:
  1. Heat shock protein homolog SSE1
The deposited structure of PDB entry 3d2f contains 2 copies of CATH domain 2.60.34.10 (Substrate Binding Domain Of DNAk; Chain A, domain 1) in Heat shock protein homolog SSE1. Showing 1 copy in chain A.
SCOP SCOP annotation
53068
Class: Alpha and beta proteins (a/b)
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Occurring in:
  1. Heat shock 70 kDa protein 1A
The deposited structure of PDB entry 3d2f contains 4 copies of SCOP domain 53068 (Actin/HSP70) in Heat shock 70 kDa protein 1A. Showing 2 copies in chain B.

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