EC 2.1.3.2: Aspartate carbamoyltransferase
Reaction catalysed:
Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate
Systematic name:
Carbamoyl-phosphate:L-aspartate carbamoyltransferase
Alternative Name(s):
- ATCase
- Aspartate carbamyltransferase
- Aspartate transcarbamoylase
- Aspartate transcarbamylase
- Aspartic acid transcarbamoylase
- Aspartic carbamyltransferase
- Aspartic transcarbamylase
- Carbamoylaspartotranskinase
- Carbamylaspartotranskinase
- L-aspartate transcarbamoylase
- L-aspartate transcarbamylase
EC 3.5.2.3: Dihydroorotase
Reaction catalysed:
(S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate
Systematic name:
(S)-dihydroorotate amidohydrolase
Alternative Name(s):
- Carbamoylaspartic dehydrase
- DHOase
- Dihydroorotate hydrolase
GO terms
Biochemical function:
- carboxyl- or carbamoyltransferase activity
- transferase activity
- amino acid binding
- aspartate carbamoyltransferase activity
- metal ion binding
- hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
- hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
- hydrolase activity
- zinc ion binding
- dihydroorotase activity
- allantoinase activity
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
IPR006131
Domain description:
Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain
Occurring in:
Occurring in:
IPR006132
Domain description:
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding
Occurring in:
Occurring in:
Structure domains
CATH domains
3.40.50.1370
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Rossmann fold
Homology:
Aspartate/ornithine carbamoyltransferase
Occurring in:
2.30.40.10
Class:
Mainly Beta
Architecture:
Roll
Topology:
Urease, subunit C; domain 1
Homology:
Urease, subunit C, domain 1
Occurring in:
