› 3db5

X-ray diffraction
2.15Å resolution

Crystal structure of methyltransferase domain of human PR domain-containing protein 4

Released:
DOI: 10.2210/pdb3db5/pdb
PDB entry 3db5 coloured by chain, front view.
PDB entry 3db5 coloured by chain, side view.
PDB entry 3db5 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Amaya MF, Zeng H, Loppnau P, Bountra C, Weigelt J, Arrowsmith CH, Edwards AM, Bochkarev A, Min J, Plotnikov AN, Wu H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-577524 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PR domain zinc finger protein 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 151 amino acids
Theoretical weight: 17.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9UKN5 (Residues: 390-540; Coverage: 19%)
Gene names: PFM1, PRDM4
Sequence domains:
Structure domains: SET domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E DW
Spacegroup: I422
Unit cell:
a: 107.294Å b: 107.294Å c: 133.642Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.222 0.298
Expression system: Escherichia coli BL21

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