› 3dc4

X-ray diffraction
1.9Å resolution

Crystal structure of the Drosophila kinesin family member NOD in complex with ADP

Released:
DOI: 10.2210/pdb3dc4/pdb
PDB entry 3dc4 coloured by chain, front view.
PDB entry 3dc4 coloured by chain, side view.
PDB entry 3dc4 coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement.
Cochran JC, Sindelar CV, Mulko NK, Collins KA, Kong SE, Hawley RS, Kull FJ
Cell 136 110-22 (2009)
PMID: 19135893

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148292 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein Nod Chain: A
Molecule details ›
Chain: A
Length: 344 amino acids
Theoretical weight: 38.31 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: P18105 (Residues: 1-318; Coverage: 48%)
Gene names: CG1763, NODA, nod
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P212121
Unit cell:
a: 47.829Å b: 75.715Å c: 94.58Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.227 0.255
Expression system: Escherichia coli

Quick links

Citations

17 review citations

Microtubule tip-interacting proteins: a view from both ends.
Jiang et al. (2011)
16 more

3 mentions without citation

ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement.
Cochran et al. (2009)
2 more