› 3dln

X-ray diffraction
1.91Å resolution

Crystal structure of the binding domain of the AMPA subunit GluR3 bound to glutamate

Released:
DOI: 10.2210/pdb3dln/pdb
PDB entry 3dln coloured by chain, front view.
PDB entry 3dln coloured by chain, side view.
PDB entry 3dln coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structure of the S1S2 glutamate binding domain of GLuR3.
Ahmed AH, Wang Q, Sondermann H, Oswald RE
Proteins 75 628-37 (2009)
PMID: 19003990

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-539158 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor 3 Chain: A
Molecule details ›
Chain: A
Length: 278 amino acids
Theoretical weight: 30.89 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P19492 (Residues: 416-530, 658-799; Coverage: 30%)
  • Best match: P19492-2 (Residues: 416-530, 658-799)
Gene names: GluA3, Glur3, Gria3
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand GLU 1 x GLU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P2221
Unit cell:
a: 47.585Å b: 47.402Å c: 137.94Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.197 0.235
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Functional insights from glutamate receptor ion channel structures.
Kumar et al. (2013)
3 more

7 mentions without citation

Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.
Hansen et al. (2021)
6 more