3do5

X-ray diffraction
2.2Å resolution

Crystal structure of Putative Homoserine Dehydrogenase (NP_069768.1) from ARCHAEOGLOBUS FULGIDUS at 2.20 A resolution

Released:
Source organism: Archaeoglobus fulgidus
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed:
L-homoserine + NAD(P)(+) = L-aspartate 4-semialdehyde + NAD(P)H
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-128110 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homoserine dehydrogenase Chain: A
Molecule details ›
Chain: A
Length: 327 amino acids
Theoretical weight: 35.96 KDa
Source organism: Archaeoglobus fulgidus
Expression system: Escherichia coli
UniProt:
  • Canonical: O29327 (Residues: 1-326; Coverage: 100%)
Gene name: AF_0935
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: C2221
Unit cell:
a: 119.107Å b: 120.818Å c: 57.886Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.188 0.221
Expression system: Escherichia coli