Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Sequence domains:
- Low-density lipoprotein (LDL) receptor class A repeat
- Picornavirus/Calicivirus coat protein
- Picornavirus capsid
- Viral coat protein subunit
- LDL receptor-like superfamily
- Low-density lipoprotein (LDL) receptor class A, conserved site
- Picornavirus coat protein VP4 superfamily
- Picornavirus coat protein VP4
Structure analysis Details
Assembly composition:
hetero 300-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138285 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Capsid protein VP1
Molecule details ›
Chain: A
Length: 289 amino acids
Theoretical weight: 32.92 KDa
Source organism: rhinovirus A2
UniProt:
Structure domains: Jelly Rolls
Length: 289 amino acids
Theoretical weight: 32.92 KDa
Source organism: rhinovirus A2
UniProt:
- Canonical:
P04936 (Residues: 568-856; Coverage: 13%)
Structure domains: Jelly Rolls
Capsid protein VP2
Molecule details ›
Chain: B
Length: 261 amino acids
Theoretical weight: 29.01 KDa
Source organism: rhinovirus A2
UniProt:
Structure domains: Jelly Rolls
Length: 261 amino acids
Theoretical weight: 29.01 KDa
Source organism: rhinovirus A2
UniProt:
- Canonical: P04936 (Residues: 70-330; Coverage: 12%)
Structure domains: Jelly Rolls
Capsid protein VP3
Capsid protein VP4
Very low-density lipoprotein receptor
