› 3dxl

X-ray diffraction
1.3Å resolution

Crystal structure of AeD7 from Aedes Aegypti

Released:
DOI: 10.2210/pdb3dxl/pdb
PDB entry 3dxl coloured by chain, front view.
PDB entry 3dxl coloured by chain, side view.
PDB entry 3dxl coloured by chain, top view.
Source organism: Aedes aegypti
Primary publication:
Multifunctionality and mechanism of ligand binding in a mosquito antiinflammatory protein.
Calvo E, Mans BJ, Ribeiro JM, Andersen JF
Proc Natl Acad Sci U S A 106 3728-33 (2009)
PMID: 19234127

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148296 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Long form salivary protein D7L1 Chain: A
Molecule details ›
Chain: A
Length: 303 amino acids
Theoretical weight: 35.12 KDa
Source organism: Aedes aegypti
Expression system: Homo sapiens
UniProt:
  • Canonical: P18153 (Residues: 20-321; Coverage: 99%)
Gene names: AAEL006424, D7, D7L1
Sequence domains: PBP/GOBP family
Structure domains: Pheromone/general odorant binding protein domain

Ligands and Environments

3 bound ligands:
Ligand CL 1 x CL
Ligand TRS 1 x TRS
Ligand GOL 4 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 49.892Å b: 65.477Å c: 52.047Å
α: 90° β: 112.74° γ: 90°
R-values:
R R work R free
0.189 0.187 0.214
Expression system: Homo sapiens

Quick links

Citations

14 review citations

Soluble proteins of chemical communication: an overview across arthropods.
Pelosi et al. (2014)
13 more

9 mentions without citation

Structure of allergens and structure based epitope predictions.
Dall'antonia et al. (2014)
8 more