EC 3.4.22.29: Picornain 2A
Reaction catalysed:
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
Systematic name:
-
Alternative Name(s):
- 2A protease
- 2A proteinase
- Picornaviral 2A proteinase
- Picornavirus endopeptidase 2A
- Poliovirus protease 2A
- Poliovirus protease 2A-Pro
- Poliovirus proteinase 2A
- Protease 2A
- Proteinase 2A-Pro
- Rhinovirus protease 2A
- Y-G proteinase 2A
EC 3.6.1.15: Nucleoside-triphosphate phosphatase
Reaction catalysed:
NTP + H(2)O = NDP + phosphate
Systematic name:
Unspecific diphosphate phosphohydrolase
Alternative Name(s):
- NTPase
- Nucleoside 5-triphosphatase
- Nucleoside triphosphate hydrolase
- Nucleoside triphosphate phosphohydrolase
- Nucleoside-5-triphosphate phosphohydrolase
- Nucleoside-triphosphatase
EC 3.4.22.28: Picornain 3C
Reaction catalysed:
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Alternative Name(s):
- 3C protease
- 3C proteinase
- Coxsackievirus 3C proteinase
- Cysteine proteinase 3C
- Foot-and-mouth protease 3C
- Foot-and-mouth-disease virus proteinase 3C
- Hepatitis A virus 3C proteinase
- Picornavirus endopeptidase 3C
- Poliovirus protease 3C
- Poliovirus proteinase 3C
- Protease 3C
- Rhinovirus protease 3C
- Rhinovirus proteinase 3C
- Tomato ringspot nepovirus 3C-related protease
EC 2.7.7.48: RNA-directed RNA polymerase
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Systematic name:
Nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
Alternative Name(s):
- 3D polymerase
- PB1 proteins
- PB2 proteins
- Phage f2 replicase
- Polymerase L
- Q-beta replicase
- RDRP
- RNA nucleotidyltransferase (RNA-directed)
- RNA replicase
- RNA synthetase
- RNA transcriptase
- RNA-dependent RNA polymerase
- RNA-dependent RNA replicase
- RNA-dependent ribonucleate nucleotidyltransferase
- Ribonucleic acid replicase
- Ribonucleic acid-dependent ribonucleate nucleotidyltransferase
- Ribonucleic acid-dependent ribonucleic acid polymerase
- Ribonucleic replicase
- Ribonucleic synthetase
- Transcriptase
GO terms
Biochemical function:
Biological process:
- not assigned
Protein families (Pfam)![The deposited structure of PDB entry 3epf contains 1 copy of Pfam domain PF00073 (picornavirus capsid protein) in Capsid protein VP1. Showing 1 copy in chain B [auth 1].](https://www.ebi.ac.uk/pdbe/static/entry/3epf_2_1_Pfam_PF00073_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3epf</span> contains 1 copy of Pfam domain <span class='highlight'>PF00073 (picornavirus capsid protein)</span> in <span class='highlight'>Capsid protein VP1</span>. Showing 1 copy in chain <span class='highlight'>B [auth 1]</span>.")
![The deposited structure of PDB entry 3epf contains 1 copy of Pfam domain PF00073 (picornavirus capsid protein) in Capsid protein VP2. Showing 1 copy in chain C [auth 2].](https://www.ebi.ac.uk/pdbe/static/entry/3epf_3_2_Pfam_PF00073_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3epf</span> contains 1 copy of Pfam domain <span class='highlight'>PF00073 (picornavirus capsid protein)</span> in <span class='highlight'>Capsid protein VP2</span>. Showing 1 copy in chain <span class='highlight'>C [auth 2]</span>.")
![The deposited structure of PDB entry 3epf contains 1 copy of Pfam domain PF00073 (picornavirus capsid protein) in Capsid protein VP3. Showing 1 copy in chain E [auth 3].](https://www.ebi.ac.uk/pdbe/static/entry/3epf_5_3_Pfam_PF00073_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3epf</span> contains 1 copy of Pfam domain <span class='highlight'>PF00073 (picornavirus capsid protein)</span> in <span class='highlight'>Capsid protein VP3</span>. Showing 1 copy in chain <span class='highlight'>E [auth 3]</span>.")
![The deposited structure of PDB entry 3epf contains 1 copy of Pfam domain PF08205 (CD80-like C2-set immunoglobulin domain ) in Poliovirus receptor. Showing 1 copy in chain A [auth R].](https://www.ebi.ac.uk/pdbe/static/entry/3epf_1_R_Pfam_PF08205_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3epf</span> contains 1 copy of Pfam domain <span class='highlight'>PF08205 (CD80-like C2-set immunoglobulin domain )</span> in <span class='highlight'>Poliovirus receptor</span>. Showing 1 copy in chain <span class='highlight'>A [auth R]</span>.")
![The deposited structure of PDB entry 3epf contains 1 copy of Pfam domain PF07686 (Immunoglobulin V-set domain) in Poliovirus receptor. Showing 1 copy in chain A [auth R].](https://www.ebi.ac.uk/pdbe/static/entry/3epf_1_R_Pfam_PF07686_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3epf</span> contains 1 copy of Pfam domain <span class='highlight'>PF07686 (Immunoglobulin V-set domain)</span> in <span class='highlight'>Poliovirus receptor</span>. Showing 1 copy in chain <span class='highlight'>A [auth R]</span>.")
![The deposited structure of PDB entry 3epf contains 1 copy of Pfam domain PF02226 (Picornavirus coat protein (VP4)) in Capsid protein VP4. Showing 1 copy in chain D [auth 4].](https://www.ebi.ac.uk/pdbe/static/entry/3epf_4_4_Pfam_PF02226_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>3epf</span> contains 1 copy of Pfam domain <span class='highlight'>PF02226 (Picornavirus coat protein (VP4))</span> in <span class='highlight'>Capsid protein VP4</span>. Showing 1 copy in chain <span class='highlight'>D [auth 4]</span>.")
InterPro annotations