3eys

X-ray diffraction
1.95Å resolution

PFA1 Fab fragment complexed with pyro-Glu3-A-Beta (3-8)

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-499868 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chain: L
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 24.2 KDa
Source organism: Mus musculus
Expression system: Mus musculus
UniProt:
  • Canonical: A2NHM3 (Residues: 1-219; Coverage: 100%)
Gene names: Igk-C, Igkc
Sequence domains:
Structure domains: Immunoglobulins
PFA1 Fab Heavy Chain Chain: H
Molecule details ›
Chain: H
Length: 223 amino acids
Theoretical weight: 23.84 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins
pyro-Glu3-A-Beta (3-8) peptide Chain: Q
Molecule details ›
Chain: Q
Length: 6 amino acids
Theoretical weight: 774 Da

Ligands and Environments

1 bound ligand:
2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: P1
Unit cell:
a: 41.656Å b: 42.677Å c: 58.63Å
α: 96.14° β: 93.83° γ: 91.73°
R-values:
R R work R free
0.207 0.204 0.256
Expression system: Mus musculus