› 3eyx

X-ray diffraction
2.04Å resolution

Crystal structure of Carbonic Anhydrase Nce103 from Saccharomyces cerevisiae

Released:
DOI: 10.2210/pdb3eyx/pdb
PDB entry 3eyx coloured by chain, front view.
PDB entry 3eyx coloured by chain, side view.
PDB entry 3eyx coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural insights into the substrate tunnel of Saccharomyces cerevisiae carbonic anhydrase Nce103.
Teng YB, Jiang YL, He YX, He WW, Lian FM, Chen Y, Zhou CZ
OpenAccess logo BMC Struct Biol 9 67 (2009)
PMID: 19852838

Function and Biology Details

Reaction catalysed: 
H(2)CO(3) = CO(2) + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156830 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase Chains: A, B
Molecule details ›
Chains: A, B
Length: 216 amino acids
Theoretical weight: 24.56 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P53615 (Residues: 14-221; Coverage: 94%)
Gene names: N2695, NCE103, NCE3, YNL036W
Sequence domains: Carbonic anhydrase
Structure domains: Carbonic anhydrase

Ligands and Environments

3 bound ligands:
Ligand ZN 2 x ZN
Ligand ACT 2 x ACT
Ligand EDO 4 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2221
Unit cell:
a: 60.57Å b: 155.73Å c: 89.69Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.197 0.241
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Gates of enzymes.
Gora et al. (2013)
2 more

6 mentions without citation

Phenols and Polyphenols as Carbonic Anhydrase Inhibitors.
Karioti et al. (2016)
5 more