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C2 Crystal form of mite allergen DER P 1

Source organism: Dermatophagoides pteronyssinus
Biochemical function: cysteine-type peptidase activity
Biological process: proteolysis
Cellular component: not assigned

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EC 3.4.22.65: Peptidase 1 (mite)

Reaction catalysed:
Broad endopeptidase specificity
Systematic name:
-
Alternative Name(s):
  • Allergen Der f 1
  • Allergen Der p 1
  • Antigen Der p 1
  • Antigen Eur m 1
  • Antigen Pso o 1
  • Der f 1
  • Der p 1
  • Endopeptidase 1 (mite)
  • Eur m 1
  • Major mite fecal allergen Der p 1

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00112
Domain description: Papain family cysteine protease
Occurring in:
  1. Der p 1 allergen
The deposited structure of PDB entry 3f5v contains 2 copies of Pfam domain PF00112 (Papain family cysteine protease) in Der p 1 allergen. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000668
Domain description: Peptidase C1A, papain C-terminal
Occurring in:
  1. Der p 1 allergen
IPR025661
Domain description: Cysteine peptidase, asparagine active site
Occurring in:
  1. Der p 1 allergen
IPR025660
Domain description: Cysteine peptidase, histidine active site
Occurring in:
  1. Der p 1 allergen
IPR000169
Domain description: Cysteine peptidase, cysteine active site
Occurring in:
  1. Der p 1 allergen
IPR013128
Domain description: Peptidase C1A
Occurring in:
  1. Der p 1 allergen
IPR039417
Domain description: Papain-like cysteine endopeptidase
Occurring in:
  1. Der p 1 allergen
IPR038765
Domain description: Papain-like cysteine peptidase superfamily
Occurring in:
  1. Der p 1 allergen

Structure domain

CATH CATH domain
3.90.70.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Cathepsin B; Chain A
Homology: Cysteine proteinases
Occurring in:
  1. Der p 1 allergen
The deposited structure of PDB entry 3f5v contains 2 copies of CATH domain 3.90.70.10 (Cathepsin B; Chain A) in Der p 1 allergen. Showing 1 copy in chain A.

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