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Crystal structure of the GAP-related domain of IQGAP1

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: regulation of GTPase activity
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00616
Domain description: GTPase-activator protein for Ras-like GTPase
Occurring in:
  1. Ras GTPase-activating-like protein IQGAP1
The deposited structure of PDB entry 3fay contains 1 copy of Pfam domain PF00616 (GTPase-activator protein for Ras-like GTPase) in Ras GTPase-activating-like protein IQGAP1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001936
Domain description: Ras GTPase-activating domain
Occurring in:
  1. Ras GTPase-activating-like protein IQGAP1
IPR008936
Domain description: Rho GTPase activation protein
Occurring in:
  1. Ras GTPase-activating-like protein IQGAP1
IPR023152
Domain description: Ras GTPase-activating protein, conserved site
Occurring in:
  1. Ras GTPase-activating-like protein IQGAP1

Structure domain

CATH CATH domain
1.10.506.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: GTPase Activation - p120GAP; domain 1
Homology: GTPase Activation - p120gap; domain 1
Occurring in:
  1. Ras GTPase-activating-like protein IQGAP1
The deposited structure of PDB entry 3fay contains 1 copy of CATH domain 1.10.506.10 (GTPase Activation - p120GAP; domain 1) in Ras GTPase-activating-like protein IQGAP1. Showing 1 copy in chain A.

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