› 3fe5

X-ray diffraction
2.51Å resolution

Crystal structure of 3-hydroxyanthranilate 3,4-dioxygenase from bovine kidney

Released:
DOI: 10.2210/pdb3fe5/pdb
PDB entry 3fe5 coloured by chain, front view.
PDB entry 3fe5 coloured by chain, side view.
PDB entry 3fe5 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystal structure of bovine 3-hydroxyanthranilate 3,4-dioxygenase.
Dilović I, Gliubich F, Malpeli G, Zanotti G, Matković-Calogović D
Biopolymers 91 1189-95 (2009)
PMID: 19226621

Function and Biology Details

Reaction catalysed: 
3-hydroxyanthranilate + O(2) = 2-amino-3-carboxymuconate semialdehyde
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-555632 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-hydroxyanthranilate 3,4-dioxygenase Chain: A
Molecule details ›
Chain: A
Length: 285 amino acids
Theoretical weight: 32.45 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: Q0VCA8 (Residues: 2-286; Coverage: 100%)
Gene name: HAAO
Sequence domains: 3-hydroxyanthranilic acid dioxygenase
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
Ligand FE 1 x FE
1 modified residue:
Ligand CSO 3 x CSO

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P1
Unit cell:
a: 40.25Å b: 42.52Å c: 46.48Å
α: 91.7° β: 113.3° γ: 107.7°
R-values:
R R work R free
0.167 0.163 0.24

Quick links

Citations

1 review citation

Ring-cleaving dioxygenases with a cupin fold.
Fetzner S. (2012)
8 other articles

2 mentions without citation

Chemical approaches to detect and analyze protein sulfenic acids.
Furdui et al. (2014)
1 more