Function and Biology

Crystal Structure of HdmX bound to the p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-6-Cl-Trp-Glu-Ac3c-Leu-NH2 at 1.33A

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: regulation of cell cycle
Cellular component: nucleus

GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence family

InterPro InterPro annotations
IPR003121
Domain description: SWIB/MDM2 domain
Occurring in:
  1. Protein Mdm4
IPR036885
Domain description: SWIB/MDM2 domain superfamily
Occurring in:
  1. Protein Mdm4
IPR016495
Domain description: p53 negative regulator Mdm2/Mdm4
Occurring in:
  1. Protein Mdm4

Structure domain

CATH CATH domain
1.10.245.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: MDM2
Homology: SWIB/MDM2 domain
Occurring in:
  1. Protein Mdm4
The deposited structure of PDB entry 3fea contains 1 copy of CATH domain 1.10.245.10 (MDM2) in Protein Mdm4. Showing 1 copy in chain A.