› 3fgw

X-ray diffraction
2.8Å resolution

One chain form of the 66.3 kDa protein

Released:
DOI: 10.2210/pdb3fgw/pdb
PDB entry 3fgw coloured by chain, front view.
PDB entry 3fgw coloured by chain, side view.
PDB entry 3fgw coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography.
Lakomek K, Dickmanns A, Kettwig M, Urlaub H, Ficner R, Lübke T
OpenAccess logo BMC Struct Biol 9 56 (2009)
PMID: 19706171

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174812 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Putative phospholipase B-like 2 Chain: A
Molecule details ›
Chain: A
Length: 559 amino acids
Theoretical weight: 63.19 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q3TCN2 (Residues: 47-594; Coverage: 100%)
Gene name: Plbd2
Sequence domains: Phospholipase B
Structure domains: Penicillin V Acylase; Chain A

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
4 bound ligands:
Ligand NAG 3 x NAG
Ligand GOL 3 x GOL
Ligand IOD 7 x IOD
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: C2
Unit cell:
a: 146.69Å b: 88.11Å c: 73.55Å
α: 90° β: 111.1° γ: 90°
R-values:
R R work R free
0.224 0.223 0.249
Expression system: Homo sapiens

Quick links

Citations

2 review citations

The proteome of lysosomes.
Schröder et al. (2010)
1 more

2 mentions without citation

Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography.
Lakomek et al. (2009)
1 more