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Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor 3-aminobenzoic acid

Source organism: Homo sapiens
Biochemical function: NAD+-protein poly-ADP-ribosyltransferase activity
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00644
Domain description: Poly(ADP-ribose) polymerase catalytic domain
Occurring in:
  1. Protein mono-ADP-ribosyltransferase PARP3
The deposited structure of PDB entry 3fhb contains 1 copy of Pfam domain PF00644 (Poly(ADP-ribose) polymerase catalytic domain) in Protein mono-ADP-ribosyltransferase PARP3. Showing 1 copy in chain A.

PF02877
Domain description: Poly(ADP-ribose) polymerase, regulatory domain
Occurring in:
  1. Protein mono-ADP-ribosyltransferase PARP3
The deposited structure of PDB entry 3fhb contains 1 copy of Pfam domain PF02877 (Poly(ADP-ribose) polymerase, regulatory domain) in Protein mono-ADP-ribosyltransferase PARP3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR012317
Domain description: Poly(ADP-ribose) polymerase, catalytic domain
Occurring in:
  1. Protein mono-ADP-ribosyltransferase PARP3
IPR004102
Domain description: Poly(ADP-ribose) polymerase, regulatory domain
Occurring in:
  1. Protein mono-ADP-ribosyltransferase PARP3
IPR036616
Domain description: Poly(ADP-ribose) polymerase, regulatory domain superfamily
Occurring in:
  1. Protein mono-ADP-ribosyltransferase PARP3

Structure domains

CATH CATH domains
3.90.228.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Phosphoenolpyruvate Carboxykinase; domain 3
Homology: Phosphoenolpyruvate Carboxykinase; domain 3
Occurring in:
  1. Protein mono-ADP-ribosyltransferase PARP3
The deposited structure of PDB entry 3fhb contains 1 copy of CATH domain 3.90.228.10 (Phosphoenolpyruvate Carboxykinase; domain 3) in Protein mono-ADP-ribosyltransferase PARP3. Showing 1 copy in chain A.
1.20.142.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Poly(ADP-ribose) Polymerase; domain 1
Homology: Poly(ADP-ribose) polymerase, regulatory domain
Occurring in:
  1. Protein mono-ADP-ribosyltransferase PARP3
The deposited structure of PDB entry 3fhb contains 1 copy of CATH domain 1.20.142.10 (Poly(ADP-ribose) Polymerase; domain 1) in Protein mono-ADP-ribosyltransferase PARP3. Showing 1 copy in chain A.

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