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Crystal structure of human Intersectin 2 RhoGEF domain

Source organism: Homo sapiens
Biochemical function: guanyl-nucleotide exchange factor activity
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00621
Domain description: RhoGEF domain
Occurring in:
  1. Intersectin-2
The deposited structure of PDB entry 3gf9 contains 1 copy of Pfam domain PF00621 (RhoGEF domain) in Intersectin-2. Showing 1 copy in chain A.

PF14604
Domain description: Variant SH3 domain
Occurring in:
  1. Intersectin-2
The deposited structure of PDB entry 3gf9 contains 1 copy of Pfam domain PF14604 (Variant SH3 domain) in Intersectin-2. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

InterPro InterPro annotations
IPR001452
Domain description: SH3 domain
Occurring in:
  1. Intersectin-2
IPR000219
Domain description: Dbl homology domain
Occurring in:
  1. Intersectin-2
IPR035899
Domain description: Dbl homology (DH) domain superfamily
Occurring in:
  1. Intersectin-2
IPR035741
Domain description: Intersectin-2, fifth SH3 domain
Occurring in:
  1. Intersectin-2
IPR036028
Domain description: SH3-like domain superfamily
Occurring in:
  1. Intersectin-2

Structure domain

CATH CATH domain
1.20.900.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Dbl Homology Domain; Chain A
Homology: Dbl homology (DH) domain
Occurring in:
  1. Intersectin-2
The deposited structure of PDB entry 3gf9 contains 1 copy of CATH domain 1.20.900.10 (Dbl Homology Domain; Chain A) in Intersectin-2. Showing 1 copy in chain A.

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