Function and Biology

Crystal structure of human RanGDP-Nup153ZnF34 complex

Source organisms:
Biochemical function: pre-miRNA binding
Biological process: protein localization to nucleolus
Cellular component: Flemming body

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00641
Domain description: Zn-finger in Ran binding protein and others
Occurring in:
  1. Nuclear pore complex protein Nup153
The deposited structure of PDB entry 3gj8 contains 4 copies of Pfam domain PF00641 (Zn-finger in Ran binding protein and others) in Nuclear pore complex protein Nup153. Showing 2 copies in chain B (some of the copies are out of the observed residue ranges!).

PF00071
Domain description: Ras family
Occurring in:
  1. GTP-binding nuclear protein Ran
The deposited structure of PDB entry 3gj8 contains 2 copies of Pfam domain PF00071 (Ras family) in GTP-binding nuclear protein Ran. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002041
Domain description: Ran GTPase
Occurring in:
  1. GTP-binding nuclear protein Ran
IPR001876
Domain description: Zinc finger, RanBP2-type
Occurring in:
  1. Nuclear pore complex protein Nup153
IPR001806
Domain description: Small GTPase
Occurring in:
  1. GTP-binding nuclear protein Ran
IPR036443
Domain description: Zinc finger, RanBP2-type superfamily
Occurring in:
  1. Nuclear pore complex protein Nup153
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. GTP-binding nuclear protein Ran
IPR026054
Domain description: Nuclear pore complex protein
Occurring in:
  1. Nuclear pore complex protein Nup153
IPR005225
Domain description: Small GTP-binding domain
Occurring in:
  1. GTP-binding nuclear protein Ran

Structure domain

CATH CATH domain
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. GTP-binding nuclear protein Ran
The deposited structure of PDB entry 3gj8 contains 2 copies of CATH domain 3.40.50.300 (Rossmann fold) in GTP-binding nuclear protein Ran. Showing 1 copy in chain A.