Function and Biology

Crystal structure of the antagonist form of human glucocorticoid receptor

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00104
Domain description: Ligand-binding domain of nuclear hormone receptor
Occurring in:
  1. Glucocorticoid receptor
The deposited structure of PDB entry 3h52 contains 4 copies of Pfam domain PF00104 (Ligand-binding domain of nuclear hormone receptor) in Glucocorticoid receptor. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR001723
Domain description: Nuclear hormone receptor
Occurring in:
  1. Glucocorticoid receptor
IPR000536
Domain description: Nuclear hormone receptor, ligand-binding domain
Occurring in:
  1. Glucocorticoid receptor
IPR035500
Domain description: Nuclear hormone receptor-like domain superfamily
Occurring in:
  1. Glucocorticoid receptor

Structure domains

CATH CATH domains
1.10.565.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Retinoid X Receptor
Homology: Retinoid X Receptor
Occurring in:
  1. Glucocorticoid receptor
The deposited structure of PDB entry 3h52 contains 4 copies of CATH domain 1.10.565.10 (Retinoid X Receptor) in Glucocorticoid receptor. Showing 1 copy in chain B.
6.10.250.340
Class: Special
Architecture: Helix non-globular
Topology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Occurring in:
  1. Glucocorticoid receptor
The deposited structure of PDB entry 3h52 contains 1 copy of CATH domain 6.10.250.340 (Single alpha-helices involved in coiled-coils or other helix-helix interfaces) in Glucocorticoid receptor. Showing 1 copy in chain A.