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Crystal Structure of ScaR with bound Cd2+

Source organism: Streptococcus gordonii
Biochemical function: protein dimerization activity
Biological process: regulation of DNA-templated transcription
Cellular component: cytoplasm

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF04023
Domain description: FeoA domain
Occurring in:
  1. Manganese transport regulator
The deposited structure of PDB entry 3hrt contains 2 copies of Pfam domain PF04023 (FeoA domain) in HTH dtxR-type domain-containing protein. Showing 1 copy in chain A.

PF02742
Domain description: Iron dependent repressor, metal binding and dimerisation domain
Occurring in:
  1. Manganese transport regulator
The deposited structure of PDB entry 3hrt contains 2 copies of Pfam domain PF02742 (Iron dependent repressor, metal binding and dimerisation domain) in HTH dtxR-type domain-containing protein. Showing 1 copy in chain A.

PF01325
Domain description: Iron dependent repressor, N-terminal DNA binding domain
Occurring in:
  1. Manganese transport regulator
The deposited structure of PDB entry 3hrt contains 2 copies of Pfam domain PF01325 (Iron dependent repressor, N-terminal DNA binding domain) in HTH dtxR-type domain-containing protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR007167
Domain description: Ferrous iron transporter FeoA-like domain
Occurring in:
  1. Manganese transport regulator
IPR022687
Domain description: DTXR-type HTH domain
Occurring in:
  1. Manganese transport regulator
IPR008988
Domain description: Transcriptional repressor, C-terminal
Occurring in:
  1. Manganese transport regulator
IPR038157
Domain description: Ferrous iron transporter, core domain
Occurring in:
  1. Manganese transport regulator
IPR036421
Domain description: Iron dependent repressor, metal binding and dimerisation domain superfamily
Occurring in:
  1. Manganese transport regulator
IPR001367
Domain description: Iron dependent repressor, metal binding and dimerisation domain
Occurring in:
  1. Manganese transport regulator
IPR022689
Domain description: Iron dependent repressor
Occurring in:
  1. Manganese transport regulator
IPR036390
Domain description: Winged helix DNA-binding domain superfamily
Occurring in:
  1. Manganese transport regulator
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. Manganese transport regulator

Structure domains

CATH CATH domains
2.30.30.90
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 type barrels.
Occurring in:
  1. Manganese transport regulator
The deposited structure of PDB entry 3hrt contains 2 copies of CATH domain 2.30.30.90 (SH3 type barrels.) in HTH dtxR-type domain-containing protein. Showing 1 copy in chain A.
1.10.10.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Occurring in:
  1. Manganese transport regulator
The deposited structure of PDB entry 3hrt contains 2 copies of CATH domain 1.10.10.10 (Arc Repressor Mutant, subunit A) in HTH dtxR-type domain-containing protein. Showing 1 copy in chain A.

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