Function and Biology

Structure of the cytosolic domain of E. coli FeoB, nucleotide-free form

Source organism: Escherichia coli
Biochemical function: ferrous iron transmembrane transporter activity
Biological process: iron ion transport
Cellular component: membrane

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF17910
Domain description: FeoB cytosolic helical domain
Occurring in:
  1. Fe(2+) transporter FeoB
The deposited structure of PDB entry 3i8s contains 3 copies of Pfam domain PF17910 (FeoB cytosolic helical domain) in Fe(2+) transporter FeoB. Showing 1 copy in chain B.

PF02421
Domain description: Ferrous iron transport protein B
Occurring in:
  1. Fe(2+) transporter FeoB
The deposited structure of PDB entry 3i8s contains 3 copies of Pfam domain PF02421 (Ferrous iron transport protein B) in Fe(2+) transporter FeoB. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR030389
Domain description: FeoB-type guanine nucleotide-binding (G) domain
Occurring in:
  1. Fe(2+) transporter FeoB
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Fe(2+) transporter FeoB
IPR041069
Domain description: FeoB, cytosolic helical domain
Occurring in:
  1. Fe(2+) transporter FeoB
IPR003373
Domain description: Ferrous iron transport protein B
Occurring in:
  1. Fe(2+) transporter FeoB
IPR005225
Domain description: Small GTP-binding domain
Occurring in:
  1. Fe(2+) transporter FeoB

Structure domains

CATH CATH domains
1.10.287.1770
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helix Hairpins
Homology: Helix Hairpins
Occurring in:
  1. Fe(2+) transporter FeoB
The deposited structure of PDB entry 3i8s contains 3 copies of CATH domain 1.10.287.1770 (Helix Hairpins) in Fe(2+) transporter FeoB. Showing 1 copy in chain B.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Fe(2+) transporter FeoB
The deposited structure of PDB entry 3i8s contains 3 copies of CATH domain 3.40.50.300 (Rossmann fold) in Fe(2+) transporter FeoB. Showing 1 copy in chain B.