› 3ibv

X-ray diffraction
3.1Å resolution

Karyopherin cytosolic state

Released:
DOI: 10.2210/pdb3ibv/pdb
PDB entry 3ibv coloured by chain, front view.
PDB entry 3ibv coloured by chain, side view.
PDB entry 3ibv coloured by chain, top view.
Source organism: Schizosaccharomyces pombe
Primary publication:
Structures of the tRNA export factor in the nuclear and cytosolic states.
Cook AG, Fukuhara N, Jinek M, Conti E
Nature 461 60-5 (2009)
PMID: 19680239

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131704 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exportin-T Chains: A, B
Molecule details ›
Chains: A, B
Length: 980 amino acids
Theoretical weight: 110.35 KDa
Source organism: Schizosaccharomyces pombe
Expression system: Escherichia coli
UniProt:
  • Canonical: O94258 (Residues: 1-978; Coverage: 100%)
Gene names: SPBP8B7.09c, los1
Sequence domains:
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA, SLS BEAMLINE X10SA
Spacegroup: P21212
Unit cell:
a: 119.9Å b: 130.1Å c: 173.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.275 0.275 0.313
Expression system: Escherichia coli

Quick links

Citations

22 review citations

tRNA biology charges to the front.
Phizicky et al. (2010)
21 more

3 mentions without citation

Karyopherin-mediated nucleocytoplasmic transport.
Wing et al. (2022)
2 more