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1.55 Angstrom Resolution Crystal Structure of Peptidase T (pepT-1) from Bacillus anthracis str. 'Ames Ancestor'.

Source organism: Bacillus anthracis str. 'Ames Ancestor'
Biochemical function: metal ion binding
Biological process: peptide catabolic process
Cellular component: cytosol

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EC 3.4.11.4: Tripeptide aminopeptidase

Reaction catalysed:
Release of the N-terminal residue from a tripeptide.
Alternative Name(s):
  • Alanine-phenylalanine-proline arylamidase
  • Aminoexotripeptidase
  • Aminotripeptidase
  • Imidoendopeptidase
  • Lymphopeptidase
  • Peptidase B
  • Peptidase T
  • Tripeptidase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF07687
Domain description: Peptidase dimerisation domain
Occurring in:
  1. Peptidase T
The deposited structure of PDB entry 3ife contains 1 copy of Pfam domain PF07687 (Peptidase dimerisation domain) in Peptidase T. Showing 1 copy in chain A.

PF01546
Domain description: Peptidase family M20/M25/M40
Occurring in:
  1. Peptidase T
The deposited structure of PDB entry 3ife contains 1 copy of Pfam domain PF01546 (Peptidase family M20/M25/M40) in Peptidase T. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR010161
Domain description: Peptidase M20B, tripeptide aminopeptidase
Occurring in:
  1. Peptidase T
IPR001261
Domain description: ArgE/DapE/ACY1/CPG2/YscS, conserved site
Occurring in:
  1. Peptidase T
IPR036264
Domain description: Bacterial exopeptidase dimerisation domain
Occurring in:
  1. Peptidase T
IPR011650
Domain description: Peptidase M20, dimerisation domain
Occurring in:
  1. Peptidase T
IPR002933
Domain description: Peptidase M20
Occurring in:
  1. Peptidase T

Structure domains

CATH CATH domains
3.40.630.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Aminopeptidase
Homology: Zn peptidases
Occurring in:
  1. Peptidase T
The deposited structure of PDB entry 3ife contains 1 copy of CATH domain 3.40.630.10 (Aminopeptidase) in Peptidase T. Showing 1 copy in chain A.
3.30.70.360
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Alpha-Beta Plaits
Homology: Alpha-Beta Plaits
Occurring in:
  1. Peptidase T
The deposited structure of PDB entry 3ife contains 1 copy of CATH domain 3.30.70.360 (Alpha-Beta Plaits) in Peptidase T. Showing 1 copy in chain A.

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