3j25

Electron Microscopy
7.2Å resolution

Structural basis for TetM-mediated tetracycline resistance

Released:
Source organism: Enterococcus faecalis
Primary publication:
Structural basis for TetM-mediated tetracycline resistance.
Proc Natl Acad Sci U S A 109 16900-5 (2012)
PMID: 23027944
Related structures: EMD-2183

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-175273 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tetracycline resistance protein TetM from transposon TnFO1 Chain: A
Molecule details ›
Chain: A
Length: 638 amino acids
Theoretical weight: 72.44 KDa
Source organism: Enterococcus faecalis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q47810 (Residues: 2-639; Coverage: 100%)
Gene names: tet(M), tetM
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 7.2Å
Relevant EMDB volumes: EMD-2183
Expression system: Escherichia coli BL21(DE3)