Function and Biology

Pseudo-atomic model of the Aquaporin-0/Calmodulin complex derived from electron microscopy

Source organisms:
Biochemical function: cell adhesion mediator activity
Biological process: gap junction-mediated intercellular transport
Cellular component: membrane

Sequence families

Pfam Protein families (Pfam)
PF13499
Domain description: EF-hand domain pair
Occurring in:
  1. Calmodulin-1
The deposited structure of PDB entry 3j41 contains 4 copies of Pfam domain PF13499 (EF-hand domain pair) in Calmodulin-1. Showing 2 copies in chain E.

PF00230
Domain description: Major intrinsic protein
Occurring in:
  1. Lens fiber major intrinsic protein
The deposited structure of PDB entry 3j41 contains 4 copies of Pfam domain PF00230 (Major intrinsic protein) in Lens fiber major intrinsic protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000425
Domain description: Major intrinsic protein
Occurring in:
  1. Lens fiber major intrinsic protein
IPR002048
Domain description: EF-hand domain
Occurring in:
  1. Calmodulin-1
IPR018247
Domain description: EF-Hand 1, calcium-binding site
Occurring in:
  1. Calmodulin-1
IPR023271
Domain description: Aquaporin-like
Occurring in:
  1. Lens fiber major intrinsic protein
IPR022357
Domain description: Major intrinsic protein, conserved site
Occurring in:
  1. Lens fiber major intrinsic protein
IPR034294
Domain description: Aquaporin transporter
Occurring in:
  1. Lens fiber major intrinsic protein
IPR011992
Domain description: EF-hand domain pair
Occurring in:
  1. Calmodulin-1