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Complex of poliovirus with VHH PVSP6A

Electron Microscopy
4.7Å resolution
PDB entry 3jbd coloured by chain, front view.
PDB entry 3jbd coloured by chain, side view.
PDB entry 3jbd coloured by chain, top view.
Source organisms:
Assembly composition:
hetero 300-mer (preferred)
Entry contents: 5 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Capsid protein VP4 and IG-heavy chain
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Multimeric state: hetero 300-mer
PDBe Complex ID: PDB-CPX-208896

Macromolecules

Capsid protein VP1
Chain: 1
Length: 302 amino acids
Theoretical weight: 33.49 KDa
Source organism: Human poliovirus 1 Mahoney
UniProt:
  • Canonical: P03300 (Residues: 580-881; Coverage: 14%)
Pfam: picornavirus capsid protein
InterPro:
Capsid protein VP1 in PDB entry 3jbd, assembly 1, front view.
Capsid protein VP1 in PDB entry 3jbd, assembly 1, side view.
Capsid protein VP1 in PDB entry 3jbd, assembly 1, top view.
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Capsid protein VP2
Chain: 2
Length: 272 amino acids
Theoretical weight: 30.08 KDa
Source organism: Human poliovirus 1 Mahoney
UniProt:
  • Canonical: P03300 (Residues: 70-341; Coverage: 12%)
Pfam: picornavirus capsid protein
InterPro:
Capsid protein VP2 in PDB entry 3jbd, assembly 1, front view.
Capsid protein VP2 in PDB entry 3jbd, assembly 1, side view.
Capsid protein VP2 in PDB entry 3jbd, assembly 1, top view.
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Capsid protein VP3
Chain: 3
Length: 237 amino acids
Theoretical weight: 26.42 KDa
Source organism: Human poliovirus 1 Mahoney
UniProt:
  • Canonical: P03300 (Residues: 342-578; Coverage: 11%)
Pfam: picornavirus capsid protein
InterPro:
Capsid protein VP3 in PDB entry 3jbd, assembly 1, front view.
Capsid protein VP3 in PDB entry 3jbd, assembly 1, side view.
Capsid protein VP3 in PDB entry 3jbd, assembly 1, top view.
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Capsid protein VP4
Chain: 4
Length: 69 amino acids
Theoretical weight: 7.6 KDa
Source organism: Human poliovirus 1 Mahoney
UniProt:
  • Canonical: P03300 (Residues: 2-69; Coverage: 3%)
Pfam: Picornavirus coat protein (VP4)
InterPro:
Capsid protein VP4 in PDB entry 3jbd, assembly 1, front view.
Capsid protein VP4 in PDB entry 3jbd, assembly 1, side view.
Capsid protein VP4 in PDB entry 3jbd, assembly 1, top view.
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nanobody VHH PVSP6A
Chain: 7
Length: 126 amino acids
Theoretical weight: 13.85 KDa
Source organism: Camelus dromedarius
Expression system: Escherichia coli
InterPro:
nanobody VHH PVSP6A in PDB entry 3jbd, assembly 1, front view.
nanobody VHH PVSP6A in PDB entry 3jbd, assembly 1, side view.
nanobody VHH PVSP6A in PDB entry 3jbd, assembly 1, top view.
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