› 3jcg

Electron Microscopy
7.06Å resolution

Cryo-EM structure of the magnesium channel CorA in the magnesium-free, asymmetric open state I

Released:
DOI: 10.2210/pdb3jcg/pdb
PDB entry 3jcg coloured by chain, front view.
PDB entry 3jcg coloured by chain, side view.
PDB entry 3jcg coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Matthies D, Dalmas O, Borgnia MJ, Dominik PK, Merk A, Rao P, Reddy BG, Islam S, Bartesaghi A, Perozo E, Subramaniam S
Cell 164 747-56 (2016)
PMID: 26871634
Related structures: EMD-6552

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194571 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cobalt/magnesium transport protein CorA Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 351 amino acids
Theoretical weight: 41.5 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9WZ31 (Residues: 1-351; Coverage: 100%)
Gene names: TM_0561, corA
Sequence domains: CorA-like Mg2+ transporter protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 7.06Å
Relevant EMDB volumes: EMD-6552
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

19 review citations

Nanodiscs for structural and functional studies of membrane proteins.
Denisov et al. (2016)
18 more

7 mentions without citation

Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Matthies et al. (2016)
6 more