Function and Biology

Crystal structure of nucleoside diphosphate kinase family protein from Babesia bovis

Source organism: Babesia bovis T2Bo
Biochemical function: kinase activity
Biological process: phosphorylation
Cellular component: not assigned

EC 2.7.4.6: Nucleoside-diphosphate kinase

Reaction catalysed:
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate
Systematic name:
ATP:nucleoside-diphosphate phosphotransferase
Alternative Name(s):
  • NDK
  • Nucleoside 5'-diphosphate kinase
  • Nucleoside 5'-diphosphate phosphotransferase
  • Nucleoside diphosphate (UDP) kinase
  • Nucleoside diphosphokinase
  • Nucleotide phosphate kinase
  • UDP kinase
  • Uridine diphosphate kinase

Sequence family

Pfam Protein family (Pfam)
PF00334
Domain description: Nucleoside diphosphate kinase
Occurring in:
  1. nucleoside-diphosphate kinase
The deposited structure of PDB entry 3js9 contains 3 copies of Pfam domain PF00334 (Nucleoside diphosphate kinase) in Nucleoside diphosphate kinase-like domain-containing protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001564
Domain description: Nucleoside diphosphate kinase
Occurring in:
  1. nucleoside-diphosphate kinase
IPR034907
Domain description: Nucleoside diphosphate kinase-like domain
Occurring in:
  1. nucleoside-diphosphate kinase
IPR036850
Domain description: Nucleoside diphosphate kinase-like domain superfamily
Occurring in:
  1. nucleoside-diphosphate kinase

Structure domain

CATH CATH domain
3.30.70.141
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Alpha-Beta Plaits
Homology: Nucleoside diphosphate kinase-like domain
Occurring in:
  1. nucleoside-diphosphate kinase
The deposited structure of PDB entry 3js9 contains 3 copies of CATH domain 3.30.70.141 (Alpha-Beta Plaits) in Nucleoside diphosphate kinase-like domain-containing protein. Showing 1 copy in chain A.