Function and Biology Details
Reaction catalysed:
Degradation of blood coagulation factors Va and VIIIa.
Biochemical function:
Biological process:
- not assigned
Cellular component:
Sequence domains:
- Gamma-carboxyglutamic acid-rich (GLA) domain
- Gamma-carboxyglutamic acid-rich (GLA) domain superfamily
- Coagulation factor-like, Gla domain superfamily
- MHC classes I/II-like antigen recognition protein
- MHC class I-like antigen recognition-like
- MHC class I-like antigen recognition-like superfamily
- Endothelial protein C receptor
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-528084 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Endothelial protein C receptor
Molecule details ›
Chains: A, B
Length: 193 amino acids
Theoretical weight: 22.05 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: MHC-I family domain
Structure domains: MHC class I-like antigen recognition-like
Length: 193 amino acids
Theoretical weight: 22.05 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
Q9UNN8 (Residues: 18-210; Coverage: 87%)
Sequence domains: MHC-I family domain
Structure domains: MHC class I-like antigen recognition-like
Vitamin K-dependent protein C light chain
Molecule details ›
Chains: C, D
Length: 33 amino acids
Theoretical weight: 4.36 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Length: 33 amino acids
Theoretical weight: 4.36 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P04070 (Residues: 43-75; Coverage: 7%)
Sequence domains: Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
