EC 2.7.11.21: Polo kinase
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Systematic name:
ATP:protein phosphotransferase (spindle-pole-dependent)
Alternative Name(s):
- Cdc5
- Cdc5p
- PLK
- POLO kinase
- Plk
- Plk1
- Plo1
- Polo serine-threonine kinase
- Polo-like kinase
- Polo-like kinase 1
- STK21
- Serine/threonine-specific Drosophila kinase polo
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence family
Protein family (Pfam)
InterPro annotations
Structure domains
CATH domains
1.10.510.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
Transferase(Phosphotransferase); domain 1
Homology:
Transferase(Phosphotransferase) domain 1
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>3kb7</span> contains 1 copy of CATH domain <span class='highlight'>1.10.510.10 (Transferase(Phosphotransferase); domain 1)</span> in <span class='highlight'>Serine/threonine-protein kinase PLK1</span>. Showing 1 copy in chain <span class='highlight'>A</span>. The deposited structure of PDB entry 3kb7 contains 1 copy of CATH domain 1.10.510.10 (Transferase(Phosphotransferase); domain 1) in Serine/threonine-protein kinase PLK1. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/3kb7_1_A_CATH_1.10.510.10_image-200x200.png)