Function and Biology Details
Reactions catalysed:
Adenosine-5'-diphospho-5'-(DNA) + H(2)O = AMP + phospho-5'-(DNA)
(DNA)-3'-diphospho-5'-guanosine + H(2)O = (DNA)-3'-phosphate + GMP
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Aprataxin (preferred)
PDBe Complex ID:
PDB-CPX-182239 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aprataxin
Molecule details ›
Chain: A
Length: 102 amino acids
Theoretical weight: 11.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: FHA domain
Structure domains: Tumour Suppressor Smad4
Length: 102 amino acids
Theoretical weight: 11.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q7Z2E3 (Residues: 15-116; Coverage: 29%)
Sequence domains: FHA domain
Structure domains: Tumour Suppressor Smad4
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU
Spacegroup:
C2
Expression system: Escherichia coli BL21(DE3)
