EC 2.7.11.26: [Tau protein] kinase
Reaction catalysed:
ATP + [tau protein] = ADP + [tau protein] phosphate
Systematic name:
ATP:[tau-protein] O-phosphotransferase
Alternative Name(s):
- ATP:tau-protein O-phosphotransferase
- Brain protein kinase PK40erk
- CDK5/p23
- Cdk5/p20
- GSK
- Glycogen synthase kinase-3-beta
- Protein tau kinase
- STK31
- TPK
- TPK I
- TPK II
- TTK
- Tau kinase
- Tau-protein kinase I
- Tau-protein kinase II
- Tau-tubulin kinase
- [Tau-protein] kinase
EC 2.7.11.1: Non-specific serine/threonine protein kinase
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Systematic name:
ATP:protein phosphotransferase (non-specific)
Alternative Name(s):
- A-kinase
- AP50 kinase
- ATP-protein transphosphorylase
- Beta-IIPKC
- Beta-adrenergic receptor kinase
- CK-2
- CKI
- CKII
- Calcium-dependent protein kinase C
- Calcium/phospholipid-dependent protein kinase
- Casein kinase
- Casein kinase (phosphorylating)
- Casein kinase 2
- Casein kinase I
- Casein kinase II
- Cyclic AMP-dependent protein kinase
- Cyclic AMP-dependent protein kinase A
- Cyclic monophosphate-dependent protein kinase
- Cyclic nucleotide-dependent protein kinase
- Cyclin-dependent kinase
- Cytidine 3',5'-cyclic monophosphate-responsive protein kinase
- Dsk1
- Epsilon PKC
- Glycogen synthase A kinase
- Glycogen synthase a kinase
- Glycogen synthase kinase
- HIPK2
- Hpr kinase
- Hydroxyalkyl-protein kinase
- M phase-specific cdc2 kinase
- MAPK
- Mitogen-activated S6 kinase
- Mitogen-activated protein kinase
- P82 kinase
- PKA
- PKC
- Phosphorylase B kinase kinase
- Phosphorylase b kinase kinase
- Phosphorylase b kinase kinase
- Protein glutamyl kinase
- Protein kinase (phosphorylating)
- Protein kinase A
- Protein kinase CK2
- Protein kinase p58
- Protein phosphokinase
- Protein serine kinase
- Protein serine-threonine kinase
- Protein-aspartyl kinase
- Protein-cysteine kinase
- Protein-serine kinase
- Prp4 protein kinase
- Raf kinase
- Raf-1
- Ribosomal S6 protein kinase
- Ribosomal protein S6 kinase II
- STK32
- Serine kinase
- Serine protein kinase
- Serine(threonine) protein kinase
- Serine-specific protein kinase
- Serine/threonine protein kinase
- T-antigen kinase
- Threonine-specific protein kinase
- Twitchin kinase
- Type-2 casein kinase
- WEE1Hu
- Wee 1-like kinase
- Wee-kinase
- cAMP-dependent protein kinase
- cAMP-dependent protein kinase A
- cGMP-dependent protein kinase
GO terms
Biochemical function:
- protein serine kinase activity
- scaffold protein binding
- RNA polymerase II-specific DNA-binding transcription factor binding
- NF-kappaB binding
- tau-protein kinase activity
- tau protein binding
- dynactin binding
- protein kinase A catalytic subunit binding
- ubiquitin protein ligase binding
- protein kinase binding
- transferase activity
- kinase activity
- beta-catenin binding
- ATP binding
- protein binding
- protein serine/threonine kinase activity
- protein kinase activity
- p53 binding
- protease binding
- nucleotide binding
Biological process:
- negative regulation of mesenchymal stem cell differentiation
- negative regulation of glycogen (starch) synthase activity
- negative regulation of type B pancreatic cell development
- positive regulation of protein localization to centrosome
- cellular response to amyloid-beta
- negative regulation of dopaminergic neuron differentiation
- negative regulation of TORC2 signaling
- positive regulation of protein localization to cilium
- negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
- positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
- regulation of long-term synaptic potentiation
- negative regulation of protein localization to nucleus
- regulation of cellular response to heat
- beta-arrestin-dependent dopamine receptor signaling pathway
- regulation of microtubule anchoring at centrosome
- neuron projection organization
- presynaptic modulation of chemical synaptic transmission
- extrinsic apoptotic signaling pathway in absence of ligand
- extrinsic apoptotic signaling pathway
- negative regulation of canonical Wnt signaling pathway
- cellular response to retinoic acid
- superior temporal gyrus development
- negative regulation of calcineurin-NFAT signaling cascade
- regulation of microtubule cytoskeleton organization
- excitatory postsynaptic potential
- canonical Wnt signaling pathway
- negative regulation of developmental process
- regulation of axonogenesis
- regulation of dendrite morphogenesis
- rhythmic process
- positive regulation of protein export from nucleus
- regulation of protein export from nucleus
- protein autophosphorylation
- positive regulation of protein catabolic process
- positive regulation of cilium assembly
- negative regulation of glycogen biosynthetic process
- negative regulation of osteoblast differentiation
- positive regulation of cell differentiation
- positive regulation of neuron apoptotic process
- proteasome-mediated ubiquitin-dependent protein catabolic process
- negative regulation of apoptotic process
- regulation of circadian rhythm
- cellular response to interleukin-3
- intracellular signal transduction
- response to endoplasmic reticulum stress
- regulation of microtubule-based process
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process
- positive regulation of protein binding
- negative regulation of TOR signaling
- positive regulation of protein ubiquitination
- positive regulation of protein-containing complex assembly
- negative regulation of protein-containing complex assembly
- neuron projection development
- regulation of axon extension
- negative regulation of cell migration
- cell differentiation
- maintenance of cell polarity
- establishment of cell polarity
- hippocampus development
- viral protein processing
- peptidyl-serine phosphorylation
- Wnt signaling pathway
- regulation of neuron projection development
- negative regulation of epithelial to mesenchymal transition
- negative regulation of gene expression
- positive regulation of gene expression
- positive regulation of autophagy
- negative regulation of signal transduction
- insulin receptor signaling pathway
- circadian rhythm
- nervous system development
- mitochondrion organization
- ER overload response
- protein phosphorylation
- glycogen metabolic process
- heart valve development
- positive regulation of cell-matrix adhesion
- epithelial to mesenchymal transition
Cellular component:
Sequence family
Protein family (Pfam)
InterPro annotations
Structure domains
CATH domains
1.10.510.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
Transferase(Phosphotransferase); domain 1
Homology:
Transferase(Phosphotransferase) domain 1
Occurring in:
