Function and Biology

Crystal structure of the Ferredoxin:NADP+ reductase from maize root at 1.7 angstroms - Test Set Withheld

Source organism: Zea mays
Biochemical function: NADPH binding
Biological process: electron transport chain
Cellular component: not assigned

EC 1.18.1.2: Ferredoxin--NADP(+) reductase

Reaction catalysed:
2 reduced ferredoxin + NADP(+) + H(+) = 2 oxidized ferredoxin + NADPH
Systematic name:
Ferredoxin:NADP(+) oxidoreductase
Alternative Name(s):
  • Ferredoxin-NADP(+) oxidoreductase
  • Ferredoxin-NADP(+) reductase
  • Ferredoxin-TPN reductase
  • Ferredoxin-nicotinamide adenine dinucleotide phosphate reductase
  • Ferredoxin-nicotinamide-adenine dinucleotide phosphate (oxidized) reductase
  • NADP(+):ferredoxin oxidoreductase
  • NADPH:ferredoxin oxidoreductase
  • TPNH-ferredoxin reductase

Sequence family

Pfam Protein family (Pfam)
PF00175
Domain description: Oxidoreductase NAD-binding domain
Occurring in:
  1. ferredoxin--NADP(+) reductase
The deposited structure of PDB entry 3lvb contains 1 copy of Pfam domain PF00175 (Oxidoreductase NAD-binding domain) in ferredoxin--NADP(+) reductase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001709
Domain description: Flavoprotein pyridine nucleotide cytochrome reductase
Occurring in:
  1. ferredoxin--NADP(+) reductase
IPR039261
Domain description: Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
Occurring in:
  1. ferredoxin--NADP(+) reductase
IPR015701
Domain description: Ferredoxin--NADP reductase
Occurring in:
  1. ferredoxin--NADP(+) reductase
IPR001433
Domain description: Oxidoreductase FAD/NAD(P)-binding
Occurring in:
  1. ferredoxin--NADP(+) reductase
IPR017927
Domain description: FAD-binding domain, ferredoxin reductase-type
Occurring in:
  1. ferredoxin--NADP(+) reductase
IPR017938
Domain description: Riboflavin synthase-like beta-barrel
Occurring in:
  1. ferredoxin--NADP(+) reductase
IPR035442
Domain description: Ferredoxin--NADP reductase, plant and Cyanobacteria type
Occurring in:
  1. ferredoxin--NADP(+) reductase

Structure domains

CATH CATH domains
3.40.50.80
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module
Occurring in:
  1. ferredoxin--NADP(+) reductase
The deposited structure of PDB entry 3lvb contains 1 copy of CATH domain 3.40.50.80 (Rossmann fold) in ferredoxin--NADP(+) reductase. Showing 1 copy in chain A.
2.40.30.10
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Elongation Factor Tu (Ef-tu); domain 3
Homology: Translation factors
Occurring in:
  1. ferredoxin--NADP(+) reductase
The deposited structure of PDB entry 3lvb contains 1 copy of CATH domain 2.40.30.10 (Elongation Factor Tu (Ef-tu); domain 3) in ferredoxin--NADP(+) reductase. Showing 1 copy in chain A.