Function and Biology Details
Reaction catalysed:
(1a) L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- TusA-like domain
- Sulfur carrier protein TusA
- TusA-like domain superfamily
- Cysteine desulfurase IscS
- Aminotransferase class-V, pyridoxal-phosphate binding site
- Pyridoxal phosphate-dependent transferase, major domain
- Pyridoxal phosphate-dependent transferase
- Pyridoxal phosphate-dependent transferase, small domain
2 more domains
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141292 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cysteine desulfurase IscS
Molecule details ›
Chain: A
Length: 423 amino acids
Theoretical weight: 47.33 KDa
Source organism: Escherichia coli O157:H7 str. EDL933
Expression system: Escherichia coli
UniProt:
Sequence domains: Aminotransferase class-V
Structure domains:
Length: 423 amino acids
Theoretical weight: 47.33 KDa
Source organism: Escherichia coli O157:H7 str. EDL933
Expression system: Escherichia coli
UniProt:
- Canonical:
P0A6B9 (Residues: 1-404; Coverage: 100%)
Sequence domains: Aminotransferase class-V
Structure domains:
Sulfur carrier protein TusA
Molecule details ›
Chain: B
Length: 82 amino acids
Theoretical weight: 9.12 KDa
Source organism: Escherichia coli O157:H7 str. EDL933
Expression system: Escherichia coli
UniProt:
Sequence domains: Sulfurtransferase TusA
Structure domains: TusA-like domain
Length: 82 amino acids
Theoretical weight: 9.12 KDa
Source organism: Escherichia coli O157:H7 str. EDL933
Expression system: Escherichia coli
UniProt:
- Canonical: P0A892 (Residues: 2-81; Coverage: 99%)
Sequence domains: Sulfurtransferase TusA
Structure domains: TusA-like domain
