› 3mc0

X-ray diffraction
2Å resolution

Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain

Released:
DOI: 10.2210/pdb3mc0/pdb
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PDB entry 3mc0 coloured by chain, front view.
PDB entry 3mc0 coloured by chain, side view.
PDB entry 3mc0 coloured by chain, top view.
Source organisms:
Primary publication:
Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.
Fernández MM, Cho S, De Marzi MC, Kerzic MC, Robinson H, Mariuzza RA, Malchiodi EL
J Biol Chem 286 1189-95 (2011)
PMID: 21059660

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106899 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig-like domain-containing protein Chains: A, C
Molecule details ›
Chains: A, C
Length: 109 amino acids
Theoretical weight: 11.77 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A2NTY6 (Residues: 31-144; Coverage: 96%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
Enterotoxin SEG Chains: B, D
Molecule details ›
Chains: B, D
Length: 239 amino acids
Theoretical weight: 27.85 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D0EMB6 (Residues: 1-233; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ACT 8 x ACT
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P3121
Unit cell:
a: 91.185Å b: 91.185Å c: 233.401Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.18 0.179 0.211
Expression system: Escherichia coli BL21(DE3)

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Citations

3 review citations

Staphylococcus aureus and its food poisoning toxins: characterization and outbreak investigation.
Hennekinne et al. (2012)
2 more

3 mentions without citation

Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.
Fernández et al. (2011)
2 more

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