Function and Biology Details
Reaction catalysed:
Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
cGMP-specific 3',5'-cyclic phosphodiesterase (preferred)
PDBe Complex ID:
PDB-CPX-131209 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
cGMP-specific 3',5'-cyclic phosphodiesterase
Molecule details ›
Chains: A, B
Length: 432 amino acids
Theoretical weight: 48.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: GAF domain
Structure domains: Beta-Lactamase
Length: 432 amino acids
Theoretical weight: 48.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
O76074 (Residues: 89-518; Coverage: 49%)
Sequence domains: GAF domain
Structure domains: Beta-Lactamase
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X29A, null
Spacegroup:
P3121
Expression system: Escherichia coli BL21
