Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Translational (tr)-type GTP-binding domain
- Elongation factor Ts, dimerisation domain superfamily
- P-loop containing nucleoside triphosphate hydrolase
- Translation elongation factor EFTu/EF1A, bacterial/organelle
- Translation elongation factor Ts, conserved site
- Translation elongation factor EFTs/EF1B
- RNA-directed RNA polymerase, catalytic domain, bacteriophage
- DNA/RNA polymerase superfamily
11 more domains
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-141406 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Elongation factor Ts; Elongation factor Tu 2
Molecule details ›
Chains: A, C
Length: 678 amino acids
Theoretical weight: 73.95 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 678 amino acids
Theoretical weight: 73.95 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P0A6P1 (Residues: 1-283; Coverage: 100%) - Canonical: P0CE48 (Residues: 1-394; Coverage: 100%)
Sequence domains:
- Elongation factor TS
- Elongation factor Tu GTP binding domain
- Elongation factor Tu domain 2
- Elongation factor Tu C-terminal domain
RNA-directed RNA polymerase subunit beta
Molecule details ›
Chains: F, G
Length: 589 amino acids
Theoretical weight: 65.6 KDa
Source organism: Qubevirus durum
Expression system: Escherichia coli BL21(DE3)
UniProt:
Length: 589 amino acids
Theoretical weight: 65.6 KDa
Source organism: Qubevirus durum
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P14647 (Residues: 1-589; Coverage: 100%)
