EC 2.3.2.27: RING-type E3 ubiquitin transferase
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Systematic name:
[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein]-L-lysine ubiquitin transferase (isopeptide bond-forming; RING-type)
Alternative Name(s):
- RING E3 ligase
- Ubiquitin transferase RING E3
EC 3.4.19.12: Ubiquitinyl hydrolase 1
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Systematic name:
-
Alternative Name(s):
- Ubiquitin C-terminal hydrolase
- Ubiquitin carboxyl-terminal hydrolase
- Ubiquitin thiolesterase
- Yeast ubiquitin hydrolase
GO terms
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Protein family (Pfam)
InterPro annotations
CATH domain