› 3naf

X-ray diffraction
3.1Å resolution

Structure of the Intracellular Gating Ring from the Human High-conductance Ca2+ gated K+ Channel (BK Channel)

Released:
DOI: 10.2210/pdb3naf/pdb
PDB entry 3naf coloured by chain, front view.
PDB entry 3naf coloured by chain, side view.
PDB entry 3naf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel.
Wu Y, Yang Y, Ye S, Jiang Y
OpenAccess logo Nature 466 393-7 (2010)
PMID: 20574420

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171393 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-activated potassium channel subunit alpha-1 Chain: A
Molecule details ›
Chain: A
Length: 798 amino acids
Theoretical weight: 89.37 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q12791 (Residues: 394-1236; Coverage: 61%)
  • Best match: Q12791-5 (Residues: 394-1178)
Gene names: KCNMA, KCNMA1, SLO
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: I422
Unit cell:
a: 134.395Å b: 134.395Å c: 231.84Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.238 0.289
Expression system: Spodoptera frugiperda

Quick links

Citations

30 review citations

Molecular Determinants of BK Channel Functional Diversity and Functioning.
Latorre et al. (2017)
29 more

38 mentions without citation

Structure of potassium channels.
Kuang et al. (2015)
37 more