EC 3.4.22.59: Caspase-6
Reaction catalysed:
Strict requirement for Asp at position P1 and has a preferred cleavage sequence of Val-Glu-His-Asp-|-
Systematic name:
-
Alternative Name(s):
- Apoptotic protease Mch-2
- CASP-6
- Mch2
GO terms
Biochemical function:
Biological process:
- hepatocyte apoptotic process
- execution phase of apoptosis
- cellular response to staurosporine
- intrinsic apoptotic signaling pathway by p53 class mediator
- pyroptotic inflammatory response
- positive regulation of necroptotic process
- protein maturation
- positive regulation of neuron apoptotic process
- regulation of programmed cell death
- positive regulation of apoptotic process
- epithelial cell differentiation
- protein autoprocessing
- apoptotic process
- proteolysis
- activation of innate immune response
Protein family (Pfam)
InterPro annotations
CATH domain