Function and Biology

Structure of N-terminal truncated Nop56/58 bound with L7Ae and box C/D RNA

Source organism: Pyrococcus furiosus DSM 3638
Biochemical function: rRNA binding
Biological process: ribosome biogenesis
Cellular component: ribonucleoprotein complex

Sequence families

Pfam Protein families (Pfam)
PF01248
Domain description: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Occurring in:
  1. Large ribosomal subunit protein eL8
The deposited structure of PDB entry 3nvi contains 2 copies of Pfam domain PF01248 (Ribosomal protein L7Ae/L30e/S12e/Gadd45 family) in Large ribosomal subunit protein eL8. Showing 1 copy in chain B.

PF01798
Domain description: snoRNA binding domain, fibrillarin
Occurring in:
  1. Nop domain-containing protein
The deposited structure of PDB entry 3nvi contains 2 copies of Pfam domain PF01798 (snoRNA binding domain, fibrillarin) in Nop domain-containing protein. Showing 1 copy in chain A.

PF21572
Domain description: Archaeal Nop5/56-rel, N-terminal domain
Occurring in:
  1. Nop domain-containing protein
The deposited structure of PDB entry 3nvi contains 2 copies of Pfam domain PF21572 (Archaeal Nop5/56-rel, N-terminal domain) in Nop domain-containing protein. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

InterPro InterPro annotations
IPR018492
Domain description: Ribosomal protein eL8/Nhp2 family
Occurring in:
  1. Large ribosomal subunit protein eL8
IPR022481
Domain description: Large ribosomal subunit protein eL8, archaea
Occurring in:
  1. Large ribosomal subunit protein eL8
IPR029064
Domain description: Ribosomal protein eL30-like superfamily
Occurring in:
  1. Large ribosomal subunit protein eL8
IPR002687
Domain description: Nop domain
Occurring in:
  1. Nop domain-containing protein
IPR004037
Domain description: Large ribosomal subunit protein eL8-like, conserved site
Occurring in:
  1. Large ribosomal subunit protein eL8
IPR004038
Domain description: Ribosomal protein eL8/eL30/eS12/Gadd45
Occurring in:
  1. Large ribosomal subunit protein eL8
IPR042239
Domain description: Nop, C-terminal domain
Occurring in:
  1. Nop domain-containing protein
IPR012976
Domain description: NOSIC
Occurring in:
  1. Nop domain-containing protein
IPR036070
Domain description: Nop domain superfamily
Occurring in:
  1. Nop domain-containing protein
IPR029012
Domain description: Helix hairpin bin domain superfamily
Occurring in:
  1. Nop domain-containing protein
IPR045056
Domain description: Nucleolar protein Nop56/Nop58
Occurring in:
  1. Nop domain-containing protein
IPR047099
Domain description: Nop5, N-terminal domain superfamily
Occurring in:
  1. Nop domain-containing protein

Structure domains

CATH CATH domains
3.30.1330.30
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: 60s Ribosomal Protein L30; Chain: A;
Homology: 60s Ribosomal Protein L30; Chain: A;
Occurring in:
  1. Large ribosomal subunit protein eL8
The deposited structure of PDB entry 3nvi contains 2 copies of CATH domain 3.30.1330.30 (60s Ribosomal Protein L30; Chain: A;) in Large ribosomal subunit protein eL8. Showing 1 copy in chain B.
1.10.246.90
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Serum Albumin; Chain A, Domain 1
Homology: Nop domain
Occurring in:
  1. Nop domain-containing protein
The deposited structure of PDB entry 3nvi contains 2 copies of CATH domain 1.10.246.90 (Serum Albumin; Chain A, Domain 1) in Nop domain-containing protein. Showing 1 copy in chain A.
1.10.287.4070
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helix Hairpins
Homology: Helix Hairpins
Occurring in:
  1. Nop domain-containing protein
The deposited structure of PDB entry 3nvi contains 2 copies of CATH domain 1.10.287.4070 (Helix Hairpins) in Nop domain-containing protein. Showing 1 copy in chain A.