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Crystal Structure of the TorS sensor domain - TorT complex in the absence of isopropanol

Source organism: Vibrio parahaemolyticus
Biochemical function: protein binding
Biological process: not assigned
Cellular component: not assigned

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EC 2.7.13.3: Histidine kinase

Reaction catalysed:
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Systematic name:
ATP:protein-L-histidine N-phosphotransferase
Alternative Name(s):
  • EnvZ
  • HK1
  • HP165
  • Histidine protein kinase
  • Protein histidine kinase
  • Protein kinase
  • Protein kinase (histidine)
  • Sln1p

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00532
Domain description: Periplasmic binding proteins and sugar binding domain of LacI family
Occurring in:
  1. Periplasmic binding protein/LacI sugar binding domain-containing protein
The deposited structure of PDB entry 3o1j contains 2 copies of Pfam domain PF00532 (Periplasmic binding proteins and sugar binding domain of LacI family) in Periplasmic binding protein/LacI sugar binding domain-containing protein. Showing 1 copy in chain C.

PF21689
Domain description: Sensor protein TorS, sensor domain
Occurring in:
  1. histidine kinase

PF22519
Domain description: TorS N-terminal sensor domain
Occurring in:
  1. histidine kinase

InterPro InterPro annotations
IPR038188
Domain description: TorS, sensor domain superfamily
Occurring in:
  1. histidine kinase
IPR028082
Domain description: Periplasmic binding protein-like I
Occurring in:
  1. Periplasmic binding protein/LacI sugar binding domain-containing protein
IPR014301
Domain description: TMAO reductase system, periplasmic protein TorT
Occurring in:
  1. Periplasmic binding protein/LacI sugar binding domain-containing protein
IPR001761
Domain description: Periplasmic binding protein/LacI sugar binding domain
Occurring in:
  1. Periplasmic binding protein/LacI sugar binding domain-containing protein
IPR037952
Domain description: Sensor histidine kinase TorS, sensor domain
Occurring in:
  1. histidine kinase

Structure domains

CATH CATH domains
3.40.50.2300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Rossmann fold
Occurring in:
  1. Periplasmic binding protein/LacI sugar binding domain-containing protein
The deposited structure of PDB entry 3o1j contains 4 copies of CATH domain 3.40.50.2300 (Rossmann fold) in Periplasmic binding protein/LacI sugar binding domain-containing protein. Showing 2 copies in chain C.
1.20.58.920
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homology: Methane Monooxygenase Hydroxylase; Chain G, domain 1
Occurring in:
  1. histidine kinase
The deposited structure of PDB entry 3o1j contains 2 copies of CATH domain 1.20.58.920 (Methane Monooxygenase Hydroxylase; Chain G, domain 1) in Phosphorelay protein LuxU. Showing 1 copy in chain A.

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