› 3om0

X-ray diffraction
1.4Å resolution

Crystal structure of the GluK5 (KA2) ATD crystallographic dimer at 1.4 Angstrom resolution

Released:
DOI: 10.2210/pdb3om0/pdb
PDB entry 3om0 coloured by chain, front view.
PDB entry 3om0 coloured by chain, side view.
PDB entry 3om0 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Crystal structures of the glutamate receptor ion channel GluK3 and GluK5 amino-terminal domains.
Kumar J, Mayer ML
J Mol Biol 404 680-96 (2010)
PMID: 20951142

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179005 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Glutamate receptor ionotropic, kainate 5 Chain: A
Molecule details ›
Chain: A
Length: 393 amino acids
Theoretical weight: 43.8 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q63273 (Residues: 20-406; Coverage: 40%)
Gene name: Grik5
Sequence domains: Receptor family ligand binding region
Structure domains: Rossmann fold

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
3 bound ligands:
Ligand NAG 4 x NAG
Ligand GOL 3 x GOL
Ligand ACT 1 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: C2221
Unit cell:
a: 66.314Å b: 101.987Å c: 116.225Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.175 0.196
Expression system: Homo sapiens

Quick links

Citations

8 review citations

Functional insights from glutamate receptor ion channel structures.
Kumar et al. (2013)
7 more

4 mentions without citation

Emerging models of glutamate receptor ion channel structure and function.
Mayer ML. (2011)
3 more