Function and Biology

Crystal structure of human galectin-1 in complex with thiodigalactoside

Source organism: Homo sapiens
Biochemical function: receptor ligand activity
Biological process: positive regulation of dendritic cell differentiation
Cellular component: galectin complex

Sequence family

Pfam Protein family (Pfam)
PF00337
Domain description: Galactoside-binding lectin
Occurring in:
  1. Galectin-1
  2. Galectin-1
The deposited structure of PDB entry 3oyw contains 1 copy of Pfam domain PF00337 (Galactoside-binding lectin) in Galectin-1. Showing 1 copy in chain A.
The deposited structure of PDB entry 3oyw contains 1 copy of Pfam domain PF00337 (Galactoside-binding lectin) in Galectin-1. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR001079
Domain description: Galectin, carbohydrate recognition domain
Occurring in:
  1. Galectin-1
  2. Galectin-1
IPR044156
Domain description: Galectin-like
Occurring in:
  1. Galectin-1
  2. Galectin-1
IPR013320
Domain description: Concanavalin A-like lectin/glucanase domain superfamily
Occurring in:
  1. Galectin-1
  2. Galectin-1

Structure domain

CATH CATH domain
2.60.120.200
Class: Mainly Beta
Architecture: Sandwich
Topology: Jelly Rolls
Homology: Jelly Rolls
Occurring in:
  1. Galectin-1
  2. Galectin-1
The deposited structure of PDB entry 3oyw contains 1 copy of CATH domain 2.60.120.200 (Jelly Rolls) in Galectin-1. Showing 1 copy in chain A.
The deposited structure of PDB entry 3oyw contains 1 copy of CATH domain 2.60.120.200 (Jelly Rolls) in Galectin-1. Showing 1 copy in chain B.