› 3p0t

X-ray diffraction
1.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HIT domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 15.13 KDa
Source organism: Mycobacterium avium subsp. paratuberculosis K-10
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q743J2 (Residues: 1-134; Coverage: 100%)
Gene name: MAP_0593c
Sequence domains: HIT domain
Structure domains: HIT-like

Ligands and Environments

2 bound ligands:
Ligand SO4 4 x SO4
Ligand EDO 8 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P43212
Unit cell:
a: 55.61Å b: 55.61Å c: 205.28Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.163 0.206
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells.
Abu-Remaileh et al. (2015)
5 more

2 mentions without citation

Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily.
Maize et al. (2013)
1 more