› › Function and Biology

Urate oxidase under 2 MPa / 20 bars pressure of nitrous oxide

Source organism: Aspergillus flavus
Biochemical function: oxidoreductase activity
Biological process: urate catabolic process
Cellular component: peroxisome

Quick links

EC 1.7.3.3: Factor independent urate hydroxylase

Reaction catalysed:
Urate + O(2) + H(2)O = 5-hydroxyisourate + H(2)O(2)
Systematic name:
Urate:oxygen oxidoreductase
Alternative Name(s):
  • Urate oxidase
  • Uric acid oxidase
  • Uricase
  • Uricase II

GO terms

Sequence family

Pfam Protein family (Pfam)
PF01014
Domain description: Uricase
Occurring in:
  1. Uricase
The deposited structure of PDB entry 3pkt contains 2 copies of Pfam domain PF01014 (Uricase) in Uricase. Showing 2 copies in chain A.

InterPro InterPro annotations
IPR002042
Domain description: Uricase
Occurring in:
  1. Uricase
IPR019842
Domain description: Uricase, conserved site
Occurring in:
  1. Uricase

Structure domain

CATH CATH domain
3.10.270.10
Class: Alpha Beta
Architecture: Roll
Topology: Urate Oxidase
Homology: Urate Oxidase;
Occurring in:
  1. Uricase
The deposited structure of PDB entry 3pkt contains 1 copy of CATH domain 3.10.270.10 (Urate Oxidase) in Uricase. Showing 1 copy in chain A.

Quick links