› 3pmi

X-ray diffraction
2.82Å resolution

PWWP Domain of Human Mutated Melanoma-Associated Antigen 1

Released:
DOI: 10.2210/pdb3pmi/pdb
Model geometry
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PDB entry 3pmi coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and histone binding ability characterizations of human PWWP domains.
Wu H, Zeng H, Lam R, Tempel W, Amaya MF, Xu C, Dombrovski L, Qiu W, Wang Y, Min J
OpenAccess logo PLoS One 6 e18919 (2011)
PMID: 21720545

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174033 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PWWP domain-containing DNA repair factor 3A Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 134 amino acids
Theoretical weight: 15.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q2TAK8 (Residues: 405-538; Coverage: 19%)
Gene names: EXPAND1, MUM1, PWWP3A
Sequence domains: MUM1-like, PWWP domain
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand SO4 2 x SO4
Ligand PEG 1 x PEG
Ligand UNL 2 x UNL
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 55.044Å b: 57.716Å c: 187.072Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.228 0.304
Expression system: Escherichia coli

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Citations

30 review citations

Perceiving the epigenetic landscape through histone readers.
Musselman et al. (2012)
29 more

3 mentions without citation

PWWP domains and their modes of sensing DNA and histone methylated lysines.
Rona et al. (2016)
2 more

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