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Crystal Structure of E.coli Dha kinase DhaK (H56N) complex with Dha

Source organism: Escherichia coli K-12
Biochemical function: phosphoenolpyruvate-glycerone phosphotransferase activity
Biological process: glycerol to glycerone phosphate metabolic process
Cellular component: transferase complex

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EC 2.7.1.121: Phosphoenolpyruvate--glycerone phosphotransferase

Reaction catalysed:
Phosphoenolpyruvate + glycerone = pyruvate + glycerone phosphate
Systematic name:
Phosphoenolpyruvate:glycerone phosphotransferase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF02733
Domain description: Dak1 domain
Occurring in:
  1. PEP-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK
The deposited structure of PDB entry 3pnq contains 4 copies of Pfam domain PF02733 (Dak1 domain) in PEP-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR004006
Domain description: DhaK domain
Occurring in:
  1. PEP-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK
IPR012736
Domain description: Dihydroxyacetone kinase DhaK, subunit 1
Occurring in:
  1. PEP-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK

Structure domains

CATH CATH domains
3.30.1180.20
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Hypothetical Protein Tm841; Chain: A;domain 3
Homology: Dihydroxyacetone kinase; domain 2
Occurring in:
  1. PEP-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK
The deposited structure of PDB entry 3pnq contains 4 copies of CATH domain 3.30.1180.20 (Hypothetical Protein Tm841; Chain: A;domain 3) in PEP-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK. Showing 1 copy in chain B.
3.40.50.10440
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Dihydroxyacetone kinase; domain 1
Occurring in:
  1. PEP-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK
The deposited structure of PDB entry 3pnq contains 4 copies of CATH domain 3.40.50.10440 (Rossmann fold) in PEP-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK. Showing 1 copy in chain B.

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