› 3psk

X-ray diffraction
2.1Å resolution

Crystal Structure of the Spt6 Tandem SH2 Domain from Saccharomyces cerevisiae, Form Native Spt6 (1247-1451)

Released:
DOI: 10.2210/pdb3psk/pdb
Model geometry
Fit model/data
PDB entry 3psk coloured by chain, front view.
PDB entry 3psk coloured by chain, side view.
PDB entry 3psk coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain.
Close D, Johnson SJ, Sdano MA, McDonald SM, Robinson H, Formosa T, Hill CP
J Mol Biol 408 697-713 (2011)
PMID: 21419780

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-150025 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription elongation factor SPT6 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 211 amino acids
Theoretical weight: 25.07 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P23615 (Residues: 1247-1451; Coverage: 14%)
Gene names: CRE2, G6169, SPT6, SSN20, YGR116W
Sequence domains: SH2 domain
Structure domains: SH2 domain

Ligands and Environments

1 bound ligand:
Ligand SO4 12 x SO4
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P212121
Unit cell:
a: 78.778Å b: 105.176Å c: 119.481Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.184 0.213
Expression system: Escherichia coli BL21

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Citations

4 review citations

Chromatin and transcription in yeast.
Rando et al. (2012)
3 more

3 mentions without citation

Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain.
Close et al. (2011)
2 more